A randomized phase III trial of olaparib tablets in patients with metastatic pancreatic cancer (mPC) and a germline BRCA1/2mutation (gBRCAm) who have not progressed following first-line chemotherapy.
A phase III randomized, open-label, multicenter trial evaluating the use of adjuvant nab-paclitaxel (nab-P) plus gemcitabine (G) versus G alone in patients with surgically resected ductal pancreatic adenocarcinoma (PDA).
Individualised Molecular Pancreatic Cancer Therapy (IMPaCT) is an Australian clinical trial looking at personalising the treatment of patients with metastatic pancreatic cancer. New protocol, standard gem or gem/abraxane followed by targeted therapy. A phase II trial assessing feasibility of personalised treatment based on tumour molecular signature in patients with recurrent or metastatic pancreatic cancer. Genomic sequencing of these loci HER2, BRCA1/BRCA2 or PALB2 and Anti EGFR.